Institute of Life Sciences
 
Introduction
 
Under the academic and research development programme, the Institute of Life Sciences was established in the main residential campus of Chhatrapati Sahu Ji Maharaja University, Kanpur in the year 1983 to impart and promote the multi and interdisciplinary higher education in the Life Sciences by utilizing the modern concepts of teaching and research at Master and Doctorate level. since its inception in imparting education at P.G. and Doctorate level and has produced a number of students in Life Sciences.
 
The courses offered by the Institute of Life Sciences is M.Sc. (Life Sciences)
 
 
SPECIAL FEATURES :
 
The faculty of Life Sciences in its course structure includes modern areas like Genetic engineering and Biotechnology, Immunology and Modern Genetics, Environment and waste recycling etc. which have direct relevant implications to serve mankind and society by the way of developing new technologies to bring drastic social changes.
 
Academic Profile of DEPARTMENT of Life Science
Established in 1982, classes started from 1984 under academic and research development Program in the residential campus of the C.S.J.M.University ( Formerly Kanpur University ) .
 
Major Focus :-
  1. To study the biological phenomenon and Life Processes in greater detail from Molecular level to organism level including its interaction with environment .
  2. To provide solid foundation for scientific principles in interdisciplinary areas related with life processes .
  3. To inculcate among the students the deep understanding of research and laboratory training .
 
Faculty Position

 

     Sanctioned

      Filled

       Professors

                02

        00

Associate Professors

                02

        01

Asst. Professors

                03

        02

Lecturer (Self-financing)

                 02

       None

 
Faculty profile with name, qualification ,
Designation and specialization
(D.Sc./D.Litt./ Ph.D./M.Phil. , etc.)
 

S/NO-

Name

Qualifi-cation

Designation

Speciali-zation

No. of Years of Expe-rience

No. of Ph.D. students guided for the last 4 years

1

Dr.Nand Lal

M.Sc.,ph.D

Professor

Plant Bio-technology

23

4

2

Dr.S.K. Awasthi

M.Sc.,Ph.D

Asst. Professor

Biochemistry & Immunology

21

4

3

Dr. Rajesh kumar

M.Sc.,Ph.D

Asst. Professor

 

Biochemistry

18

3

 
Teaching Programme :
Course being run : M.Sc. ( Life Sciences )
Duration : 2 Years divided into 4 semesters of six months each .
Intake : 40 Students
Two semesters are run simultaneously viz Ist and IIIrd , IInd and IVth semesters .
Admission : Opened to both streams Maths as well as Biosterms .
Course being run : M.Phil.( Life Sciences )
Duration : 1 Year ( Two semesters of 6 months duration)
Intake : 25 Students .
 
Course Structure :
Semester I
Physics ( Remedial )
Maths I for Biostream
Biology I ( Remedial ) for Maths stream
Biology II ( Remedial )
Chemistry
Biochemistry – I
Microbiology
Cell Biology – I
Genetics
Practical
 
Semester II
Cell Biology II
Biochemistry II
Molecular Biology
Immunology
Biophysics and Structural Biology
Animal Physiology
Plant / Microbial Physiology
Practical
 
Semester III
Developmental Biology
Bioinformatics
Molecular Genetics and Genetic Engg.
Radiation Biology
Cancer Biology
Neurophysiology
Photobiology
Virology
Advanced Microbial Physiology
Human Genetics
Advanced Plant Physiology
Maths II ( Mathematical Modeling )
 
Semester IV
Hormone and Metabolic Disorders
Plant Cell Culture
Free Radicals in Biology
Neural and Behavioral Biology
Microbial Biotechnology
Membrane Biology
Applied Molecular Biology
Molecular Parasitology
Gene Expression in Cell Differentiation and Disease
Area of specialization ( Dissertation )
  • Course Structure of M Phil( Life Sciences)
  • M Phil Life Sciences
Semester I
1. Advance Molecular Biology
2. Immunology and immunochemistry
3. Advances in Biochemistry
4. Microbial Cell Metabolism and regulation
5. Ecology and Biodiversity
 
Semester II
1. Research Methodology and Lab Technique
2. Dissertation
 
Board of Studies in Life Sciences needs every three years to incorporate the latest development in the different papers of M.Sc Life Sciences keeping in view the national and global priorities in the subject.
 
ADMISSION PROCEDURE :
Admission to M.Sc. Programme in Life Sciences is open to candidates who hold a bachelor’s degree ( TDC ) with any combination of subjects among Zoology , Botany , Chemistry , Physics and Mathematics with atleast 50% marks in aggregate .
 
The candidates will have to appear in the entrance test organised by the university and his/her admission be on the basis of the result on merit and counseling . Admission procedure tentatively begins in the month of April every year . Entrance test is held usually in May and counseling is done in the last week of June every year.
 
Admission to M.Phil. ( Life Sciences ) is opened to those who hold a M.Sc. degree in any area of biological sciences viz Life Sciences , Zoology , Botany, Biochemistry , Biotechnology , Genetics , Microbiology etc. with atleast 50% marks in aggregate .Admissions are made on the basis of merit in Entrance Test.
 
Scope and Application :
The modern fields of study provide ample employment opportunities especially in the following areas .
  1. Medical , Pharmaceutical and Biotechnology related industries .
  2. Advanced research in the field of Biochemistry , Microbiology , Immunology, Environmental Sciences and Genetic Engg & Molecular Biology , Cancer Biology , Pollution Control etc.
  3. Teaching and research in academic institution , universities and National and International labs .
  4. Avenues for placement in R & D production units of various government / public / private sector organization.
 
Fees Structure
MSc Life Sciences (Aided Course) 2 Years Course
  1. 1st Semester Rs. 6,443/- (Per Annum)
  2. 3rd Semester Rs. 7,143/- (Per Annum)
 
MPhil Life Sciences (SFS Course) 1 Year Course
  1. 1st Semester Rs. 54,443/- (Per Annum)
 
Publication:-
S.No. Name(s) of Author(s) Year Title Complete Reference
1 S.K. Awasthi, S. Kumar and A.S. Katiyar 2006 Studies on Crude Oil Degradation by Thermopholic Strains of Pseudomonas aeruginosa Indian J. Applied Pure Biol.  21:25-30
2 S. Katiyar, S.K. Awasthi and R.K. Shahu 2008 Suppression of 9L-6 level in human peripheral blood mononuclear cells stimulated with PAH/LPS after occupational exposure to chromium Sci.  Total Environ. 390:355-361
3 S. Singh, P. Singh, S.K. Awasthi, A. Pandey and L. Iyenger 2008 Mineralization of 2-aminobenzene-sulfonate by a bacterial consortium World J. Microbiol. Biotechnol.  24:841-847
4 B. Jee, V.M. Katoch and S.K. Awasthi 2008 The dissection of relationship between small heat shock proteins and mycobacterial diseases Indian J. Lepr.  80:231-245
5 S. Katiyar, S.K. Awasthi and J.K. Srivastava 2009 Effect of chromium on the level of IL-12 and IFN-gamma in occupationally exposed workers Sci. Total Environ.  407:1868-1874
6 S.K. Awasthi, M. Ashfaq and S. Singh 2009 Effect of flucose and chloramphenicol on ABS biodegradation by a bacterial consortium Biol. and Med. 2:15-19
7. Singh R.S. and Awasthi S.K. 2012 Estimation of level of catalase and glutathione peroxidise in oral cancer patents and their suppression by antioxidants, 2012 Life Science Bulletin  9(1)
8 Singh R.S., Katiyar S. and Awasthi S.K. 2012 Co-relation of free redicals and ROS in oral premalignant and malignant reasons and their suppression by antioxidants Research in Environment and Life Sciences  5(3),
9 R. Behal, R. Jain, K. K. Behal and T. N. Dhole 2008 Seroprevalence and risk factors for hepatitis B virus infection among general population in ArqGastroenterol. 45(2):137-140
10 R. Behal, R. Jain, K. K. Behal and T. N. Dhole 2010 Variation in the host ABO blood group may be associated with susceptibility to hepatitis C virus infection Epidemiology and Infection 138:1096-1099
11 Kaushik, Atul, Kaushik, Jeevan Jyoti, Kulshrestha, Richa and Lal, N. 2006 Screening of six medicinal plants used in North Indian Unorthodox Medicine for pathogenic microorganisms Natural Products: An Indian Journal 2: 65-69
12 Mishra, R. and Lal, N. 2006 Induced genetic variability and divergence in M3 generation in Mungbean (Vigna radiata (L.) Wilczek) Indian Journal of Pulses Research 19: 47-49
13 Lal, N. and Mishra, R 2006 Effect of Cadmium on germination, growth and photosynthetic pigments in Cowpea Indian Journal of Pulses Research 19: 76-78
14 Singh, Vinod P., Gupta, Parul and Lal, N. 2008 Synthesis, spectral and biological studies of some metal(II) complexes with benzil salicylaldehyde acyldihydrazones. Russian Journal of Coordination Chemistry 34: 270-277.
15 Kaushik, Atul, Kumari, M., Jyoti, Jeevan, Mittal, M., Lal, N. and Agrawal, A.C. 2009 Anti-inflammatory effect of Tectona grandis in experimental animal models. The Pharma Review (July Issue):162-164.
16 Lal, N. 2009 Biochemical alterations due to acute tannery
effluent toxicity in Lemna minor L.
Journal of Phytology 1(6): 361-368.
17 Jyoti, J., Lal, N., Lal, Ram, Kaushik, Atul 2009 Production of Thermostable and Acidophilic Amylase from Thermophilic Bacillus licheniformis JAR-26. Journal of Applied Biological Sciences 3(3):7-12.
18 Datta, Jhuma, Lal, N., Kaashyap, Mayank, Gupta, Prasoon P. 2010 Efficiency of Three PCR based Marker Systems for Detecting DNA Polymorphism in Cicerarietinum (L) and Cajanuscajan (L) Millspaugh.    Genetic Engineering and Biotechnology Journal 2010 GEBJ 5: 1-15.
19 Jyoti, Jeevan, Lal, Nand, Lal, Ram and Kaushik, Atul 2011 Partial Purification and Characterization of an Acidophilic Extracellular a-Amylase from Bacillus licheniformis JAR-26 International Journal of Advanced Biotechnology
and Research 2: 315-320.
20 Datta, Jhuma and Lal, Nand 2011 Genetic Differentiation in Cicer arietinum L. and Cajanus cajan L. Millspaugh using SSR and ISSR Marker Systems Advanced BioTech
11(5): 39-44.
21 Datta, Jhuma and Lal, Nand 2011 Characterization of Genetic Diversity in Cicer arietinum L. and Cajanus cajan L. Millspaugh using random amplified polymorphic DNA and simple sequence repeat markers Genomics and Quantitative Genetics
3: 30-41
22 Abha and Rajesh Kumar 2011 Modulation of delayed type hypersensitivity response by skin peptide from Rana tigerina Indian Journal of Science
and Technology
4:1510-1516.
23 Abha and Rajesh Kumar 2011 Induction of phagocytosis by skin peptide from Rana tigerina: Synergism between nitric oxide and hydrogen peroxide Journal of PAS (Zoological
Sciences) 17:34-47.
24 Shalini Kapoor, Rajesh Kumar and Neeraj Arora 2011 Sodium retention in hypertensive patients of different blood groups Indian Journal of Bio
Research 85(1):15-22.
25 R. Yadav, Babban Jee and S. K. Awasthi 2014 Curcumin suppresses the production of Pro-inflammatory cytokine Interlenkm – 18 in LPS stimulated murine macrophage like cells Indian Journal of medical Biochemistry (Springer ) online
26 Nirupama Lal and S.K. Awasthi 2015 A Comparative Assessment of Molecular Marker Assays ( AFLP and RAPD ) for CYMBOPOGON germplasm characterization World J. Pharma .Research Volume 4 ,
Issue 2 , 1019 - 1041
27 Nirupama Lal and S.K. Awasthi 2015 Comparative Genetic Analysis among genera CYMBOPOGON and VETIVERIA by RAPD Southern Hybridization and Sequencing World J. Pharma .Research Volume 4 ,
Issue 2 , 1442 – 1470
 
Major Research Project s :
Faculty Funding Agency Grant Received Period
S.K. Awasthi DST, New Delhi 36.81 Lacs 2009-2013
PI CST, Lucknow 6.54 Lacs 2009-2012
 
Title :Effect of Th1 and Th2 Cytokines on hspX and other responsive genes of Mycobacterium bovis BCG. (DST PROJECT)
 
Title : Effect of Thermal Shock on Survival Strategy of Mycobacterium in dormancy.(CST Project)
 
Departmental Projects :
S.N. Topic Student Supervisor  Year
1. Isolation, Optimization and Production of Esterase from Soil bacteria Mayank Vajapeyi (M.Sc.) Dr. Nand Lal 2012
2. Effect of light quality on seed germination and photosynthetic pigment biosynthesis in Vigna unguiculata (L.) Walp. Saijasi Dubey
(M.Sc.)
Dr. Nand Lal 2012
3. Effect of light quality on seed germination and photosynthetic pigment biosynthesis in Rice Oryza sativa L. Shweta Mishra
(M.Sc.)
Dr. Nand Lal 2012
4. Vernalization of garden pea Pisum sativum Akanksha Gupta
(M.Sc.)
Dr. A.L. Jatav 2012
5. Vernalization of chickpea or kabuli chana Cicer arietinum L. Prerna Gupta
(M.Sc.)
Dr. A.L. Jatav 2012
6. Use of vernalization process to determine the productivity of Cicer arietinum L. Rashi Sachan
(M.Sc.)
Dr. A.L. Jatav 2012
7. Effect of seed vernalization on yield and seed quality of wheat Triticum aestivum L. Abhishek Varma
(M.Sc.)
Dr. A.L. Jatav 2012
8. Effect of seed vernalization on yield and seed quality of field pea Pisum sativum L. Kusum Lata Kashyap
(M.Sc.)
Dr. A.L. Jatav 2012
9. Effect of seed vernalization on yield and seed quality of Barely Horduem vulgare Preeti Dixit
(M.Sc.)
Dr. A.L. Jatav 2012
10. Exploration and exploitation of soil bacteria diversity for novel antibacterials. Pooja Verma
(M.Phil.)
Dr. S.K. Awasthi 2012
11. Isolation of protease inhibitor gene from chicpea and study of protein profile of different species of chickpea Ranjeet Ram Prasad
(M.Sc.)
Dr. S.K. Awasthi 2012
12. Suppressor gene based phylogenetic analysis of Dolichos Yellow mosoic virus (DOYMV) infecting Dolichos lablab Sonam Arya
(M.Phil.)
Dr. S.K. Awasthi 2012
13. Identification of unknown bacteria and effect of antibiotic on the bacteria Priyanka Soni
(M.Sc.)
Dr. Rajesh Kumar 2012
14. Identification of unknown bacteria and effect of antibiotic on the bacteria Rashmi Pal
(M.Sc.)
Dr. Rajesh Kumar 2012
15. Identification of unknown bacteria and effect of antibiotic on the bacteria Taruna Mishra
(M.Sc.)
Dr. Rajesh Kumar 2012
16. Identification of unknown bacteria and antibiotic sensitivity test Rahul
(M.Sc.)
Dr. Rajesh Kumar 2012
17. Identification of unknown bacteria on the basis of various related biochemical tests and effects of related antibiotics over it Sonal Takiyar
(M.Sc.)
Dr. Rajesh Kumar 2012
 
Collaborative Research Programmes:
Such programmes are being run with several institutes of repute like ITRC, CDRI, IIPR, NBRI, CIMAP, SGPGI,NJIL , KGMU, FRI, G.S.V.M. Medical College and IIT Kanpur in following areas:
 
Immunology, Molecular characterisation, Biodegradation, Genome Studies, Genetic Engineering, Genetic Variation, Tissue Culture Studies, Biochemical Toxicology, Phytoremediation. Heat Shock Proteins
 
M.Sc. students as well as Ph.D students avail the opportunity of conducting training programme/project working above National Labs. These have bearings on the employment opportunities of the students in the field of advanced research.
 
Reputed Scientists in the form of Adjunct Professors from the above labs are invited to deliver Scientific talks on various aspects of Life Sciences as per the MOU Signed between the Department and their parent National Labs.
 
Some important topics of the collaborative research programme completed in last three years as follows:
 
With SGPGI, Lucknow: Maternal Immunoregulation and foetal survival, Cellular and Humoral Immune Responses against Indian Helicobacter pylori strains in experimental model, immunologicall investigations : Cellular Response and cytokine profile in workers exposed to Lead.
 
With KGMU, Lucknow: A study on the effect of various herbal hypoglycemic agents on Oxidative stress and Antioxidant status drug induced Diabetic Rats, Relevance of Free Radicals and Antioxidants enzymes in Human Hypertension.
 
With CDRI, Lucknow: Effect of altered hormonal status on glycoprotein milieu in the uterus of Rat in relation to mucolytic agents.
 
With IIT, Kanpur: Studies on the fundamental and applied aspects of anoxis phenotypic bacterial strains , Biological decoloration and degradation of Azo dyes.
 
With NJIL,Agra: Heat Shock Proteins involved in Mycobacterial Infection and dormancy
 
Academic Activities :
 
SBC Local Chapter :
A local chapter of Society of Biological Chemist (SBC, India) has been opened under the Convenorship of Dr. S. K. Awasthi, in the Institute of Life Sciences in which some invited talks have been arranged for students and faculty members. The prominent scientists who delivered their talks are as follows:
  1. Dr. Manoj Pandey (Myoclinic Rochester USA): Antiidiotypic antibodies and protection as fetal loss in parental lymphocytes immunized woman with recurrent spontaneous abortion (RSA).
  2. Dr. Pranay D. Khare (Myoclinic, Rochester, USA): Retroviral Engineering : A new hope for Gene Therapy.
  3. Prof. Surakha Agarwal (Dept. of Genetics, SGPGI, Lucknow): Human Genome
  4. Project : Science of Ethics.
 
Conference Organized :
1. A National Conference on Immunology in Health and Disease was organized by the Institute on 11-12 January 2006. The Chief Guest of the Conference was Padmashri Prof. N.K. Ganguli, D.G. Indian Council of Medical Research, New Delhi. Key Note Speech was given by Padmbhusan Prof. G.P. Talwar, Founder Director, N.I.I., new Delhi. Organizing Secretary of this DST, CSIR, ICMR Sponsored Conference was Dr. S.K. Awasthi . Approximately 800 Delegates including 10 from abroad attended the Conference. Invited Talks were delivered by 25 reputed Speakers.
 
2. 25th Biennial Conference of Indian Association of Leprologist was organized by by the department on 19-21 Nov. 2007 which included following programmes.
  1. CME on Molecular and other Interventions in the management of Mycobacterial Diseases.
  2. National symposium on Immunotherapy update with special reference to Mycobacterial Infections.
 
This reference was funded by ICMR, DST, CSIR, MCI, NAMS and WHO.
 
Placements :
  1. As scientists in various international & national labs . Like CDRI, Lucknow ITRC , Myoclinic Rochester USA.
  2. Requirement as Teacher in various P.G. Colleges & Universities .
  3. Pharmaceutical & various other industries .
  4. Post doctral fellow in leading research organization in USA , UK , Switzerland , Japan , Canada .
 
Performance in National Competitive Test : In last 3 sessions
  1. Civil services - 01
  2. Defense services – 00
  3. NET – 12
  4. SET/CET – 16
  5. GATE - 12
 
Research Facilities Available:
  1. A herbal garden with all modern faculties has been developed in the campus where several herbal medicinal plants are grown.
  2. Equipments:
    1. UV-Visible Spectrophotometer
    2. Centrifuge(Micro, Table top and Refrigerated)
    3. Deep Freezer
    4. Electronic Digital Balance
    5. Gel Electrophoresis Appratus
    6. Phase Contrast Microscope
    7. Bomb Calorimeter
    8. pH/Conductivity Meter
    9. Microtome
    10. BOD incubator
    11. Autoclave
    12. Laminar Air Flow
    13. Flame Photometer
    14. Environmental Test Chamber
    15. ELISA Reader
    16. Seed Germinator
    17. PCR
    18. Gel documentation System
 
A Central Instrumentation facility is being developed in the campus under the direct supervision of hon’able Vice Chancellor where Research Scholors from various departments including Life Sciences may avail the facilities required for advance research viz- HPLC, Gas Chromatograph, PCR, Autoanalyzer, DNA sequencer, Gel Documentation System, Double Beam UV-visible Spectrophotometer.
 
Alumini Association :
Old pass out students of M.Sc Life Sciences from this Institute meet in the month of November/December every year and discuss their research experience in the form of invited lectures in different upcoming areas of Life Sciences.
 
List Of Alumini Holding Important Position :
  1. Dr. Raj Kamal Tripathi, Scientist, Central Drug research Institute, Lucknow .
  2. Dr. Vinod Singh, Head, Deptt. of Microbiology, Barakatullah University, Bhopal
  3. Dr. Uma S. Dubey, Asstt. Professor, Department of Biological Sciences, BITS, Pilani
  4. Dr. Lalita Gupta, Asstt. Professor, Department of Biological Sciences, BITS, Pilani
  5. Dr. Amogh A. Sahastrabudhe, Scientist, Central Drug research Institute, Lucknow
  6. Dr. Poonam Singh, Scientist, Central Drug research Institute, Lucknow
  7. Dr. Preeti Srivastava, Asstt. Professor, Indian Institute of Technology, New Delhi
  8. Dr. Manisha Sachan, Asstt. Professor, Moti Lal Nehru National Institute of Technology, Allahabad
  9. Dr. Sanjeev Kumar Singh, Reader, Deptt. of Bioinformatics, Alagappa University, Karaikudi
  10. Dr. Akanksha Chaturvedi, Research Scientist, NIH, USA
  11. Dr. Divya Vats, Institut fur Biomedizinische Technik, HCI D 426.9, Wolfgang-Pauli-Str. 10, Zurich, Switzerland
  12. Dr. Rajarshi Kumar Gaur, Associate Professor, Modi Institute of Technology and Science, Lakshmangarh (Sikar)
  13. Dr. Anurag Gupta, Deptt. of Oncology, University Hospital, Zurich, Switzerland
  14. Mrs. Pratima Bajpai, Asstt. Professor, Modi Institute of Technology and Science, Lakshmangarh (Sikar)
  15. Dr. Srilekha Mistra, Asstt. Professor, Deptt. of Biotechnology, Banasthali Vidyapith, P.O. Banasthali Vidyapith, Rajasthan-22
  16. Dr. Babban Jee, Scientist C, Dept. of Health Research Ministry of Health and Family Welfare, (Govt, of India) New Delhi
 
Strength:
  1. Interdisciplinary Biology course having strong input from physical sciences.
  2. Study of Life processes with holistic approach from molecular level up to organism level in tune with environment.
  3. Wide range of papers from animal, plant and microbial systems and their interrelationships.
  4. Syllabus designed is fully in accordance with national level CSIR-NET-JRF examination.
  5. Course structure imparts knowledge of subject areas applicable in various bio-industries viz. biofertilizer production, Food and allied industries, cloning and transgenic production, diagnostics, drug discovery and drug delivery, vaccine technology, commercial biotechnology units etc.
 
Future plans of the department :
  1. Recruitment of teachers with interdisciplinary teaching and research interest on vacant faculty positions
  2. Strengthening of Laboratory training of students
  3. Promotion of in-house M.Sc./M.Phil. project works
  4. Development of inter-institutional collaboration in priority research area for Ph.D. studies and collaborative research
  5. Promotion of external faculty participation as resource persons to teach advance courses/papers
  6. Understanding the national and global priorities and in tune with the boom in Biological Sciences at International level, It is proposed to launch two new academic programmes of interdisciplinary nature in this Institute
 
1. M.Sc. (Infection Biology)
2. M.Sc. (Human Genetics)
 
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